In 1999, Indianapolis businessman Dennis Reinbold and partner Eric De Bord formed Dreyer & Reinbold Racing. The team competed in - and won - its debut race in January of 2000 at the Walt Disney World Speedway with Robbie Buhl behind the wheel. Buhl, who also started on the front row of the Indianapolis 500 in 2002, retired from racing in 2004 and became co-owner of the team with Reinbold.

Justin Wilson joined team veteran Mike Conway for the 2010 season. For the second year in a row, DRR successfully qualified four cars in the Indianapolis 500 with Ana Beatriz and Tomas Scheckter joining Conway and Wilson. Beatriz would become the highest qualified female and rookie for the 500-mile classic. Conway was sidelined for the remainder of the season following an incident in the closing laps of the 500. DRR looked to rookies Beatriz and JR Hildebrand and IZOD IndyCar Series race winners Scheckter, Paul Tracy, and Graham Rahal to fill in for Conway. Wilson would claim two second-place finishes for DRR on the street courses of St. Petersburg and Long Beach, as well as capture the pole position on the streets of Toronto, DRR's first since 2002.

DRR boats an impressive driver alumni, including Indianapolis 500 winners Buddy Lazier, Al Unser, Jr., and Buddy Rice; IZOD IndyCar Series race winner Ryan Briscoe; and the first woman to win the pole position for a major open wheel event, Sarah Fisher. Other recent drivers include Roger Yasukawa, John Andretti, and Davey Hamilton.

2011 will mark Dreyer & Reinbold Racing's 12th year of affiliation with Racing for Kids. In its 22 years, Racing For Kids representatives have visited more than 20,000 children in hospitals and local race markets across the globe.